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ISS : About Us : ISS Personnel : Ruggero De Maria Marchiano 

Ruggero De Maria Marchiano 
Research Director

Telephone: +39 +39 06 4990 3393
Viale Regina Elena 299
00161 - Roma (I)
demaria@iss.it

Publications

  1. Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R. Identification and expansion of human colon-cancer-initiating cells [letter]. Nature 2007;445(7123):111-115.
  2. Zeuner A, Pedini F, Signore M, Ruscio G, Messina C, Tafuri A, Girelli G, Peschle C, De Maria R. Increased death receptor resistance and FLIP short expression in polycythemia vera erythroid precursor cells. Blood 2006;107(9):3495-3502.
  3. Eramo A, Ricci Vitiani L, Zeuner A, Pallini R, Lotti F, Sette G, Pilozzi E, Larocca LM, Peschle C, De Maria R. Chemotherapy resistance of glioblastoma stem cells [letter]. Cell death and differentiation 2006;13(7):1238-1241.
  4. Eramo A, Pallini R, Lotti F, Sette G, Patti M, Bartucci M, Ricci Vitiani L, Signore M, Stassi G, Larocca LM, Crinò L, Peschle C, De Maria R. Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction. Cancer research 2005;65(24):11469-11477.
  5. Felli N, Pedini F, Zeuner A, Petrucci E, Testa U, Conticello C, Biffoni M, Di Cataldo A, Winkles JA, Peschle C, De Maria R. Multiple members of the TNF superfamily contribute to IFN-?- mediated inhibition of erythropoiesis. Journal of immunology 2005;175(3):1464-1472.
  6. Ricci-Vitiani L, Pedini F, Mollinari C, Condorelli G, Bonci D, Bez A, Colombo A, Parati EA, Peschle C, De Maria R. Absence of caspase 8 and high expression of PED protect primitive neural cells from cell death. Journal of experimental medicine 2004;200(10):1257-1266.
  7. Bonci D, Hahne M, Felli N, Peschle C, De Maria R. Potential role of APRIL as autocrine growth factor for megakaryocytopoiesis. Blood 2004;104(10):3169-3172.
  8. Conticello C, Pedini F, Zeuner A, Patti M, Zerilli M, Stassi G, Messina A, Peschle C, De Maria R. IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins. Journal of immunology 2004;172(9):5467-5477.
  9. Eramo A, Sargiacomo M, Ricci-Vitiani L, Todaro M, Stassi G, Messina C, Parolini I, Lotti F, Sette G, Peschle C, De Maria R. CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells. European journal of immunology 2004;34(7):1930-1940.
  10. Zeuner A, Pedini F, Signore M, Testa U, Peschle C, De Maria R. Stem cell factor erythroid precursor cells from chemotherapeutic agents via up-regulation of BCL-2 family proteins. Blood 2003;102(1):87-93.
  11. Zeuner A, Peschle C, De Maria R. Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1 [abstract]. Blood 2003;98(11 part 2):141b.
  12. Stassi G, Todaro M, Zerilli M, Ricci-Vitiani L, Di Liberto D, Patti M, Florena AM, Di Gaudio F, Di Gesù G, De Maria R. Thyroid cancer resistence to chemiotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10. Cancer research 2003;63(20):6784-6790.
  13. Conte E, Manzella L, Zeuner A, Cocchiaro G, Conticello C, Messina C, De Maria R, Messina A. Involvement of interferon regulatory factor-1 in monocyte CD95 expression and CD95-mediated apoptosis [letter]. Cell death and differentiation 2003;10(5):615-617.
  14. Stassi G, De Maria R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Nature reviews. Immunology 2002;2(3):195-204.
  15. Stassi G, De Maria R. Response to 'Thyrocytes - not innocent bystanders in autoimmune disease'. Nature immunology 2001;2(3):183.
  16. Stassi G, Zeuner A, Di Liberto D, Todaro M, Ricci-Vitiani L, De Maria R. Fas-FasL in Hashimoto's thyroiditis. Journal of clinical immunology 2001;21(1):19-23.
  17. Zeuner A, Ricci-Vitiani L, Conticello C, De Maria R. Death in 2000 ways. Cell death and differentiation 2000;7(11):1140-1144.
  18. Ricci-Vitiani L, Conticello C, Zeuner A, De Maria R. CD95/CD95L interactions and their role in autoimmunity. Apoptosis: an international journal on programmed cell death 2000;5(5):419-424.
  19. Stassi G, Di Liberto D, Todaro M, Zeuner A, Ricci-Vitiani L, Stoppacciaro A, Ruco L, Farina F. Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins. Nature immunology 2000;1(6):483-488.
  20. De Maria R, Grignani F, Testa U, Valtieri M, Ziegler BL, Peschle C. Gene regulation in normal and leukemic progenitor/stem cells. Haematologica 1999;84(EAH-4 Edu.):8-10.
  21. De Maria R, Testa U, Luchetti L, Zeuner A, Stassi G, Pelosi E, Riccioni R, Felli N, Samoggia P, Peschle C. Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis. Blood 1999;93(3):796-803.
  22. De Maria R, Zeuner A, Eramo A, Domenichelli C, Bonci D, Grignani F, Srinivasula SM, Alnemri ES, Testa U, Peschle C. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature 1999;401:489-493.
  23. Zeuner A, Eramo A, Peschle C, De Maria R. Caspase activation without death. Cell death and differentiation 1999;6:1075-1080.
  24. Ziegler BL, Valtieri M, Almedia Porada G, De Maria R, Muller R, Masella B, Gabbianelli M, Casella I, Pelosi E, Bock T, Zanjani E, Peschle C. KDR receptor: a key marker defining hematopoietic stem cells. Science 1999;285:1553-1558.
  25. De Maria R, Boirivant M, Cifone MG, Roncaioli P, Hahne M, Tschopp J, Pallone F, Santoni A, Testi R. Functional expression of Fas and Fas ligand on human gut lamina propria T Lymphocyles. Journal of clinical investigation 1996;97(2):316-322.
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