Addiction to substances such as tobacco, alcohol, drugs (including New Psychoactive Substances - NPS) and behavioral addictions (gambling, food, internet and new technologies, doping) are important risk factors for public health.

The Istituto Superiore di Sanità (ISS, the National Institute of Health in Italy) works to prevent and combat these addictions, contributes to the knowledge of phenomena from an epidemiological point of view, optimizes the pathways of diagnosis and treatment and the improvement of interventions through specific areas of research, as well as control, supervision, information, training and advice. It also advises through what is known as the Help line (telephone counseling and scientific information) on addictions and doping and offers support for improving the quality of performance of the National Health Service (NHS) pharmacology laboratories.

In particular, tobacco consumption is one of the major risk factors in the development of cancer, cardiovascular and respiratory diseases. Emerging phenomenon is also the intake of nicotine through next-generation tobacco products and e-cigarettes. Alcohol is the first substance capable of causing high social impact addiction. Drug addiction today is represented by the phenomenon of taking more classic abuse substances, including alcohol and new psychoactive substances.

Gambling disorder, food and internet addiction are behavioral addictions that in addition to causing clinically significant discomfort and/or disorders are a public health problem of increasing importance with a high impact in daily life.

Back The Joint Action on Tobacco Control 2  

The National Centre on Addiction and Doping of Istituto Superiore di Sanità (CNDD-ISS), which has already participated in the three-year project (2017-2020) of the first Joint Action on Tobacco Control (JATC 1), is the coordinator for Italy within the second Joint Action on Tobacco Control (JATC 2). Specifically, CNDD-ISS coordinates the following affiliated entities: Ministry of Health, Mario Negri Institute for Pharmacological Research (IRFMN), Oncologic network, prevention and research Institute (ISPRO). 

The Joint action on strengthening cooperation between interested Member States and the Commission in the area of tobacco control (JATC 2) was launched in October 2021, in the wake of the previous Joint action on tobacco control which ended in December 2020 ( This second European joint project is particularly necessary not only to give a definitive reinforcement to what has already been achieved with the first project, but also to further weaken the impact of tobacco use on the health of the population and consequent healthcare costs of tobacco use in Europe. 

Despite considerable progress made in recent years, the number of smokers in the EU is still high – 26% of the overall population and 29% of young Europeans aged 15-24 smoke ( 

The overall target of the JATC 2 is to strengthen the cooperation between the Member States and the European Commission within the area of tobacco control, specifically concerning enforcement and room for improvement of the Tobacco Products Directive (TPD) (, the Tobacco Advertising Directive (TAD) ( and to develop a common ground for strategies on smoke-free environments and tobacco endgame strategies.  

The partners of JATC 2 are also committed in the new Europe’s Beating Cancer Plan  ( where EU Member States stand together in the fight against tobacco, and in promoting activities consistent with the objectives of the WHO Framework Convention on Tobacco Control (FCTC) (  

This EU funded 36-month project is participated by 21 countries with 36 different institutions, organized in nine Work Packages (WPs) and coordinated by Danish Safety Technology Authority (DSTA).  

Specific activities of the Work Packages are described as follows:

  • Work Package 1 – Coordination has the objective of coordinating the overall smooth implementation of the project and ensure efficient management of the project
  • Work Package 2 – Dissemination aims at maximising the impact of the project by supporting the consultation with stakeholders and the dissemination of the project’s results to the target audiences 
  • Work Package 3 - Evaluation of the JATC 2 evaluates the outputs and outcomes of the JATC 2 and supports  the optimization of the project implementation and internal processes necessary for their achievement
  • Work Package 4 - Sustainability and Cooperation across Europe has the objective of ensuring that the results of the joint action, its outputs, activities and benefits are developed and continue after the end of the project thorough sustainable funding and resources. Specifically, the sustainability actions are aimed at the further development of the EU cooperation on tobacco control activities through knowledge sharing and dissemination of best practices 
  • Work Package 5 - EU-CEG (European Common Entry Gate) data and enhanced laboratory capacity for regulatory purposes focuses on tobacco and related products from the point of view of their characteristics as reported into the manufacturers’ notifications through the European Common Entry Gate (EU CEG) ( or analysed by independent laboratories. By acting as a focal point between end-users from Member States Competent Authorities and the European Commission, WP5 partners aim at strengthening cooperation, providing relevant tools and sustainable support to end users with regards to EUCEG data handling and product analyses, for effective enforcement of the regulations (
  • Work Package 6 - Enforcement of tobacco product regulation aims at strengthening the EU Member States’ capacities in the enforcement of tobacco product regulation at the EU Member States and EU wide level through the sharing of common experiences, challenges and solutions. The WP will establish contact with all EU authorities working with tobacco regulation to conduct a needs assessment and create a knowledge hub network. The knowledge hub network will consist of a platform for sharing knowledge and twice-yearly meetings for topics picked by member states 
  • Work Package 7 - Health impact and regulatory implications of e-cigarettes and novel tobacco products aims at enhancing the understanding of the properties, health impact and regulatory implications of novel tobacco products and e-cigarettes to support effective information and regulation. This will be accomplished by collecting and analysing data to gain insight into the variation of novel tobacco products and e-cigarettes between countries. The use, abuse potential and health risks of novel tobacco products and e-cigarettes will be evaluated. In addition, adverse effects associated with the use of novel tobacco products and e-cigarettes across the EU will be collected. The results will support EU Member States’ training, capacity building and information sharing on novel tobacco products and e-cigarettes  
  •  “Work Package 8 - Smoke-free environments and tobacco advertising, promotion, and sponsorship (TAPS) legislation in Europe” has the objective of outlining and disseminating best practices for addressing upcoming challenges to smoke-free environments in Europe (FCTC Art.8) and to assess tobacco advertisement, promotion and sponsorship (TAPS) implementation and impact in Europe (FCTC Art.13). The WP will achieve this by outlining best practices and ensuring the dissemination thereof. This WP will also gather evidence in favour of smoke-free environments to identify, adapt and assess novel challenges to smoke-free environments. Further, the WP8 will assess and create the framework for the expansion of smoke-free environments in Europe, including but not limited to outdoor areas and some private settings. Lastly, the WP will identify and share actions undertaken by Member States to address challenges for the application of the EU bans on cross-border and internet TAPS and develop the “weight of evidence” for a new TAD
  • Work Package 9 - Best practices to develop an effective and comprehensive tobacco endgame strategy” provides tools to put forward actions in line with the ‘Tobacco-Free Generation’ goal of the Europe’s Beating Cancer Plan, of less than 5% of the population using tobacco by 2040 in Europe. For this purpose, the WP identifies national tobacco endgame strategies and forward-looking tobacco control policies aiming at tobacco endgame, and assesses their feasibility for the countries in the European region, taking into account different national contexts and capacities for tobacco control. The WP will also explore and exchange best practices in the development, implementation and evaluation of these strategies and policies, and synthesize evidence and identify research needs related to new policies

The JATC 2 will contribute to the efforts to reduce the toll of tobacco-related morbidity and mortality in the European Union, through a closer cooperation and a smooth circulation of relevant information on tobacco policies and strategies between Member States. From a public health perspective, prevention, monitoring and treatment of tobacco and nicotine products use in Europe will contribute to the reduction of demand for these products, which benefits the health of the population. 

All this can be achieved in synergy with a comprehensive and successful update of the Tobacco Products Directive, the Tobacco Advertising Directive, and an effective silencing of industry interference, coherent with article 5.3 of the FCTC. 

The participation of JATC 2 at the 7th European Conference on Tobacco Control 

JATC 2 participated in the 7th European Conference on Tobacco Control (ECTC - European Conference on Tobacco Control) organized by the European Network for Smoking Prevention (ENSP), which took place in Crete (Heraklion) from 6th  to July 8th , 2022. ENSP is an international non-profit organisation, created in 1997 under Belgium law, with the following priority objectives: 

  • to implement the WHO Framework Convention on Tobacco Control (WHO-FCTC) in Europe, 
  • to reduce the prevalence of tobacco use in Europe to less than 5% by 2040. 

Experts, health professionals, researchers and stakeholders participated in the various sessions of the conference on issues related to tobacco control including: protection of the environment, tobacco taxation and public health, COVID-19 and tobacco, heated tobacco products and e-cigarettes, smoking cessation, regulating tobacco flavours, tobacco effects on health, tobacco endgame, tobacco denormalization, tobacco industry interference, youth and tobacco. 

A specific session of the Conference was also organized to present the activities and preliminary results of the 9 Work Packages of the JATC 2. 

The National Centre on Addiction and Doping of the Istituto Superiore di Santà (ISS) attended the Conference as a member of the Scientific Committee, and as chair participated in the session dedicated to JATC 2 together with the National Public Health Organization of Greece. 

The abstracts on JATC 2 Work Package activities are available at this link,11388 

National centre for addiction and doping

Tobacco and nicotine Joint Action on Tobacco Control


Dependencies Tobacco and e-cigarettes