Veterinary public health

TOPIC

Veterinary public health

Veterinary public health

The complex relationship between human health, animal populations and the environmental contexts in which they intersect, directly or through the food chain, is the cornerstone of the veterinary public health (Sanità Pubblica veterinaria, SPV) activity and the areas of veterinary medicine which contribute most to human health and well-being.

It covers multiple aspects of the human / animal relationship, such as: animal health and welfare, the development and management of veterinary drugs, veterinary intervention in the event of disasters, veterinary urban hygiene, health management of wildlife. Therefore, the SPV is a decisive component of the unitary vision of the concept of health which takes the name of One Health, a modern conception of the relationships between human, animal and environmental health.

Zoonoses, or diseases communicable from animals to humans, are one of the most consolidated areas of SPV. Over 70% of emerging human diseases have a zoonotic origin. They range from "historical" diseases such as rabies and salmonellosis, to diseases that have emerged in recent decades (ebola, SARS, HIV / AIDS, resulting from the monkey immunodeficiency virus, hepatitis E, prion diseases). The interdisciplinary approach of One Health is crucial for the study and management of zoonoses.

Priority activities of the Istituto Superiore di Sanità (ISS, the National Institute of Health in Italy) are research on the etiology, pathogenesis and epidemiology of zoonoses, in particular of those with food and vector transmission, and integrated medical-veterinary surveillance systems, also in collaboration with experimental zooprophylactic institutes. Important aspects of the ISS activity in the SPV are also the integrated approach to antibiotic resistance and the safety of veterinary drugs and feed, on which the healthiness of food of animal origin depends.

Other activities concern animal experimentation and its alternatives with the development of innovative experimental models, also in accordance with the principle of 3R (Replacement, Reduction, Refinement) and the technical-scientific evaluation activity regarding the welfare of the animals being tested.



Back E. coli Genomics: Next Generation Sequencing (NGS) applied to the study of pathogenic E. coli

The E. coli genomics section of the previous website is meant to give the user access to information related with the E. coli genomics and Next Generation Sequencing (NGS) applied to the study of pathogenic E. coli. Efforts will be done to maintain the section constantly updated with the latest releases in the sector.
Information on the updates available will be pushed to all the EU NRL through the “Focus on” mailing list and to any other user via the RSS channel, upon subscription.
This section may also feature downloadable material, including documents related with the EURL for E. coli initiatives in the field, as well as link to usable tools to perform local analyses of NGS data.
All the software and tools included in the list are freeware and are made available directly from the authors’ websites.
Additional links are provided that direct the user to the web environments where it is possible to remotely run analyses using NGS data.
This section is also the portal to access the EURL VTEC-managed Galaxy platform ARIES. It contains tools and workflows developed by the EURL for E. coli and specifically intended for analysing E. coli genomes, as well as other bioinformatics, available on the Galaxy tool shed, for a standard QC and analysis of NGS data.

Related links

Center for Genomic Epidemiology (Technical University of Denmark)
Multi Locus Sequence Typing of E. coli at the University of Warwick (Sanger sequencing)
E. coli reference genomes at NCBI
VelvetOptimizer de novo assembler by Victorian Bioinformatics Consortium for genome annotation
Sequence assembly with MIRA 4
PROKKA by Victorian Bioinformatics Consortium for genome annotation
RAST Rapid Annotation using Subsystem Technology
MAUVE Multiple Genome Alignment
BLAST Ring Image Generator (BRIG)
Galaxy CRS4 Orione (data intensive biology)
Tablet: A high-performance graphical viewer for NGS assemblies and alignments
Integrated Genome Browser (IGB). A piece of software to browse genomic data.


• Basic Course on Bioinformatics tools for NGS data mining (Rome, 11-12 June 2015)
• 2nd Course on Bioinformatics Tools for Next Generation Sequencing data mining: use of bioinformatics tools for typing pathogenic E. coli (Rome, 16-17 June 2016)
• 3rd Course on Bioinformatics Tools for Next Generation Sequencing data mining: use of bioinformatics tools for typing pathogenic E. coli (Rome, 18-19 June 2018)


Dipartimenti/Centri/Servizi

Departments Food safety, nutrition and veterinary public health

Target

Healthcare professional

Content type

Document

Topics

Nutrition and food safety Food-borne diseases Microbiological food safety Veterinary public health Zoonoses


Elenco Argomenti