Rapporto ISTISAN 21/10 - Quality assurance in intra-operative radiation therapy. Update of the Rapporto ISTISAN 03/1. Stefano Andreoli, Antonella Ciabattoni, Cinzia De Angelis, Maria Cristina Leonardi, Loris Menegotti, Maria Pimpinella, Antonella Rosi - ISS (EN)

Istituto Superiore di Sanità
Quality assurance in intra-operative radiation therapy. Update of the Rapporto ISTISAN 03/1.
Stefano Andreoli, Antonella Ciabattoni, Cinzia De Angelis, Maria Cristina Leonardi, Loris Menegotti, Maria Pimpinella, Antonella Rosi
2021, xii, 189 p. Rapporti ISTISAN 21/10 (in Italian)

In recent years the number of Italian Centres performing IntraOperative Radiation Therapy (IORT) treatments has had a large growth, going from 17 Centres at the time of the first report in the series Rapporti ISTISAN in 2003 to the 50 Centres reported in a survey of 2016. This document is the revised version of the previous one after more than ten years of IORT clinical activity in most of the centres surveyed. It illustrates the “global philosophy” of Quality Assurance in IORT, taking into account both clinical and technical, physical and dosimetric aspects. With a consolidated experience in the technique with electrons and with the most recent acquisitions related to the technique with photons, the organizational phases, the operating procedures and the related therapeutic indications of IORT are described. The report was drafted by a Working Group, coordinated by the National Institute of Health, comprising radiation oncologists and medical physicists and with the collaboration of ENEA-INMRI (Italian National Agency for New Technologies, Energy and Sustainable Economic Development- National Institute of Ionizing Radiation Metrology) for dosimetric aspects.
Key words: IntraOperative Radiation Therapy; Clinical indication; Physical and dosimetrical aspects