Summary
What is already known about this topic?
In studies with few COVID-19 cases, positive dengue virus (DENV) immunoglobulin M results were reported with various serologic tests, indicating possible cross-reactivity in serologic tests for DENV and SARS-CoV-2 infections.
What is added by this report?
In a large cohort of febrile patients in Puerto Rico (where DENV is endemic) with recently confirmed SARS-CoV-2, DENV, or Zika virus infections, the specificity of DENV and SARS-CoV-2 enzyme-linked immunosorbent assays was ≥98%.
What are the implications for public health practice?
These findings indicate that diagnoses of dengue or Zika virus diseases with the serological assays described in this report are not affected by COVID-19, nor do dengue or Zika virus diseases interfere with the diagnosis of COVID-19.
Entire content available on: https://www.cdc.gov/mmwr/volumes/71/wr/mm7110a3.htm
