Economic evaluation based on RWE, RCT and decision models - ISS (EN)

This line of activity concerns the development of statistical analyses for cost-effectiveness, cost-utility and cost-minimization, an integral part of the HTA plant.

These analyses are conducted using different approaches depending on whether data from real practice (RWE), randomized controlled trials or literature reviews or meta-analyzes are available.

In the latter case, the information available is systematized to populate a decision model that allows one to explore uncertainty by mapping alternative scenarios and projecting them over time. These analyses make it possible to attribute a profile of economic sustainability to a new technology, by comparing cost-effectiveness or cost-utility ratios with different reference thresholds.