Prevention and health promotion

TOPIC

Prevention and health promotion

Prevention and health promotion

Many scientific studies have shown the importance of prevention and health promotion to reduce the incidence of diseases and mortality and consequently the costs to the National Health Service (NHS) and society and to promote the maintenance of well-being and quality of life.

Diseases such as type 2 diabetes, certain types of cancer and dementia can be partially prevented. Nearly 80% of heart disease and strokes can be avoidable if people are willing to change their lifestyle. In a modern concept of health, its promotion and prevention must focus on joint actions in different sectors of society, mainly on modifiable behavioural risk factors and social, economic and environmental health determinants, to mention the importance of early diagnosis, the crucial role of vaccinations and the fight against inequalities.

In this area, in accordance with the policies promoted by international agencies such as the World Health Organization (WHO), adopted by national regulations, the strategic activities of the Istituto Superiore di Sanità (ISS, the National Institute of Health in Italy) are inspired by the fundamental principles of capacity building of strengthening people's skills to make responsible choices for their own well-being. In this vision, prevention and health promotion encompass all stages of life and consider health no longer the responsibility of NHS alone.

To this end, the ISS collects data and carries out research on lifestyles and behaviours with potential effects on health, it studies and promotes models of intervention, supports Ministries and Regions in disease prevention and health promotion activities, and collaborates with other national and international institutions.



Back Sovrappeso, dimagrimento, danno e riparazione del danno al DNA

 

Che relazione c’è tra eccesso ponderale e danno del DNA? Cosa succede ai meccanismi normalmente deputati alla riparazione del danno al DNA quando c’è una situazione di sovrappeso o di obesità? E cosa cambia dopo un calo ponderale? Il Registro Nazionale Gemelli, in collaborazione con il dipartimento Ambiente e Salute dell’Istituto superiore di sanità e con il dipartimento di Medicina dei Sistemi dell’Università di Roma Tor Vergata, sta studiando 16 coppie di gemelli monozigoti composte da un gemello normopeso e l’altro in sovrappeso. Si stanno indagando il danno al DNA e le proteine deputate alla sua riparazione, i profili metabolico, lipidico e infiammatorio, lo stress ossidativo e il microbioma prima e dopo il dimagramento del gemello sovrappeso a seguito di una dieta ipocalorica di alcuni mesi. Studiare due gemelli geneticamente identici ci permette di analizzare gli effetti della differenza di peso, indipendentemente dall'influenza del patrimonio genetico ereditario. Accanto alle coppie di gemelli, stiamo studiando anche 36 pazienti obesi – non gemelli - che si sottopongono a chirurgia bariatrica per perdere peso.

 

Per info
Lorenza Nisticò, Istituto Superiore di Sanità
Viale Regina Elena, 299- 00161 Roma
Email: registro.nazionale.gemelli@iss.it


Dipartimenti/Centri/Servizi

Center of reference for behavioural sciences and mental health

Topics

Chronic diseases and aging Prevention and health promotion Obesity Mental health Psychological well-being and quality of life Tumors Prevention and identification of cancer risk factors