Events
12/55 - Registro Nazionale delle Coagulopatie Congenite. Rapporto 2011.Francesca Abbonizio, Adele Giampaolo, Romano Arcieri, Hamisa Jane Hassan e Associazione Italiana Centri Emofilia (AICE)2012, iii, 63 p.
National registry of congenital bleeding disorders. Report 2011.
Francesca Abbonizio, Adele Giampaolo, Romano Arcieri, Hamisa Jane Hassan and Associazione Italiana Centri Emofilia (AICE)
2012, iii, 63 p. (in Italian)
The National registry of congenital bleeding disorders supplies epidemiological data on the prevalence of the different congenital bleeding disorders in Italy, on therapy complications, in particular infections and onset of inhibitor antibodies, and on the needs of drugs for the treatment therapy. Data collected in the Registry 2011 are relative to 51 out of 54 Italian Hemophilia Centres and refer to 8,411 subjects: 43% of these are Hemophilia A patients; 25% has von Willebrand disease, 9% Hemophilia B and 14% defects of other coagulation factors. The total number of patients with inhibitor is 379; in the population with severe Hemophilia A, 18% (298 patients) developed inhibitor during the therapy. In the analyzed patients, 256 are HIV-positive, of them 67% has severe Hemophilia A; HCV-positive patients are 1,467 in total. During 2011 the amount of Factor VIII (FVIII), estimated on the basis of data supplied, was 443,000,000 International Units (IU); the estimated consumption of Factor IX was 68,000,000 IU.
Key words: Hemophilia centres; Bleeding disorders; Hemophilia; Factor VIII; Plasma-derived products; Recombinant clotting factors
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