Events
07/13 - Esposizioni a farmaci prese in esame dal Centro Antiveleni di Milano nel 2004.Franca Davanzo, Laura Settimi, Pietro Carbone, Fabrizio Maria Sesana, Valeria Di Masi, Maurizio Bissoli, Marcello Ferruzzi, Rossana Borghini, Tania Giarratana, Angelo Travaglia, Francesca Assisi, Paola Moro, Sergio Manfrè, Fiammetta Nori, Paolo Severgnini, Ilaria Rebutti, Paolo Roazzi, Antonella Pirica, Tiziana
Exposures to pharmaceuticals handled by the Poison Control Centre of Milan (Italy), in 2004.
Franca Davanzo, Laura Settimi, Pietro Carbone, Fabrizio Maria Sesana, Valeria Di Masi, Maurizio Bissoli, Marcello Ferruzzi, Rossana Borghini, Tania Giarratana, Angelo Travaglia, Francesca Assisi, Paola Moro, Sergio Manfrè, Fiammetta Nori, Paolo Severgnini, Ilaria Rebutti, Paolo Roazzi, Antonella Pirica, Tiziana Della Puppa
2007, v, 25 p. (in Italian)
The Istituto Superiore di Sanità (the National Institute of Health in Italy) and the Poison Control Centre (PCC) of Milan, handling about 60% of the national poison exposure consultations, have recently implemented a collaborative programme aimed at setting up an ongoing systematic analysis and dissemination of the data collected by this Centre. We are now examining the information collected during the last three years. This report is focused on cases exposed to pharmaceuticals examined by the PCC of Milan in 2004. In that period the PCC handled 10,858 cases of exposure to pharmaceuticals occurred in different Italian regions. For 79% of cases the PCC was contacted by health care facilities. The peak call volume was from 4 to 11 PM. Children younger than 6 years were involved in 28% of exposure episodes and 58% of them were female. A single substance was implicated in 74% of reports. About 35% of exposures were unintentional, and 53% intentional. Therapeutic errors accounted for 9%. Clinical adverse effects related to exposure were coded in 48%, while treatment was required for 97%. The most common drug categories involved were sedative/hypnotics/antipsychotics (48%), antidepressants (20%), and analgesics (16%). Although based on the data collected by one Centre, the report provides a preliminary characterization of human toxic exposures to pharmaceuticals handled by the PCCs in Italy, and highlightes the potential of a national toxic exposure surveillance system.
Key words: Toxic exposures to pharmaceuticals, Poison Control Centres, Surveillance
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