Atterraggio
PROJECTS
NAMS4NANO - Integration of New Approach Methodologies results in chemical risk assessments: Case studies addressing nanoscale considerations
Results
05/04/2023 Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vestibulum sit amet commodo ex, nec molestie urna. Sed ut massa rhoncus, blandit odio in, porttitor risus. Maecenas porttitor mattis orci, eget tincidunt massa luctus at. Fusce feugiat metus sit amet eros egestas, nec condimentum neque venenatis. Integer molestie, sapien pellentesque efficitur sollicitudin, lectus elit efficitur risus, eget congue quam urna at tellus. Fusce nunc tellus, pul...Continue
The background
04/04/2023 The integration of data from application of New Approach Methodologies (NAMs) in chemical risk assessment is considered a critical area for the successful application of Next Generation Risk Assessment (NGRA) and for facilitating the routine use of NAMs in risk assessments. One specific area in which the European Food Safety Authority (EFSA) considers NAMs to be promising tools is the safety assessment of nanomaterials. This is a cross-cutting m...Continue
LOT 2 - Risk assessment case studies
05/04/2023 LOT 2 (Risk assessment case studies) focuses on five case studies using NAMs for addressing the nanoscale considerations and integrating this information with existing information and knowledge for conducting a risk assessment for consumers. The case studies are as follows: Conventional ZnO with a nanoscaled fraction authorized as a nutrient source and ZnO nanoparticles SiO2 (SAS) authorized as food additive (E551) Conventional iron oxides ...Continue
LOT 3 - Methodological and generic case studies
05/04/2023 LOT 3 (Methodological and generic case studies) focuses on five methodological and cross-cutting case studies. These do not cover a full risk assessment for a specific material, rather they aims to methodological progress and guidance update. The case studies are as follows: Nanopesticides: nanocarrier loaded with a pesticide active substance Nanofibres, with nanocellulose as an example ‘Aging’: simulating transformations in the GI tract to...Continue
LOT 1: Review of tools and developing a Qualification System
05/04/2023 LOT 1 (Review of tools and developing a Qualification System for NAMs) focuses on (i) complementing the EFSA NAMs roadmap with a review of available NAM-based tools and methods for assessing the toxicity of nanoparticles, in particular those developed by recent EU Research projects, and (ii) developing and implementing a proposal for a “fit for purpose qualification system for NAMs” aimed at facilitating the regulatory use of NAM tools and method...Continue
About us
04/04/2023 Team Istituto Superiore di Sanità The ISS team contributing to the project is the Nanosafety Team of the Department of Food Safety, Nutrition and Veterinary Public Health. This team is active in the areas of physicochemical characterisation, toxicology and risk assessment of nanomaterials. The team has recently coordinated the NANOCELLUP project. Scientific coordinator: Francesco Cubadda Phone: +39 06 4990 6024 Email: francesco.cubadda@i...Continue
The Project
04/04/2023 The integration of data from application of New Approach Methodologies (NAMs) in chemical risk assessment is considered a critical area for the successful application of Next Generation Risk Assessment (NGRA) and for facilitating the routine use of NAMs in risk assessments. This EFSA-funded effort is subdivided in three lots with a 4-year duration. LOT 1 and 2 are coordinated by the German federal Institute for risk assessment (BfR) and the It...Continue
